Anti-CD39 [I-392]

Absolute Antibody

Anti-CD39 [I-392]

9

The binding characterization of this antibody for CD39 expressed on Ramos cells was done using flow cytometry (WO2018065552). The binding of this antibody to various recombinant human CD39 isoforms was detected using ELISA. This antibody bound only vascular CD39, without any binding to CD39-L1, CD39-L2, CD39-L3 or CD39-L4. This antibody did not induce or increase CD39 down regulation. It was reported that this antibody is very potent at blocking CD39 enzymatic activity and is capable of neutralizing ATPase activity (US20190153113).

Flow Cytometry, ELISA, Neutralisation/Blocking

Research Use Only

Monoclonal

I-392

ENTPD1

ectonucleoside triphosphate diphosphohydrolase 1

ATP-DPH, ATPDase, CD39, NTPDase-1, SPG64, ectonucleoside triphosphate diphosphohydrolase 1, ATP diphosphohydrolase, CD39 antigen, NTPDase1, ecto-ATP diphosphohydrolase 1, ecto-ATPDase 1, ecto-ATPase 1, ecto-apyrase, lymphoid cell activation antigen, nucleoside triphosphate diphosphohydrolase 1

Rabbit

IgG

Ectonucleoside triphosphate diphosphohydrolase 1

This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG2b format for improved compatibility with existing reagents assays and techniques.

Human

-20°C,2°C to 8°C

12352203