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IHC analysis of CD68 using anti-CD68 antibody (PA1518).
IHC analysis of CD68 using anti-CD68 antibody (PA1518).
IHC analysis of CD68 using anti-CD68 antibody (PA1518).

Anti-Macrosialin CD68 Antibody Picoband(r)

Research Use Only
PA1518
Boster Bio
ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot, ImmunoHistoChemistry
Product group Antibodies
ReactivityHamster, Mouse, Rat
TargetCd68
Price on request
100 ug
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    Boster Bio
  • Product Name
    Anti-CD68 Antibody
  • Delivery Days Customer
    9
  • Antibody Specificity
    No cross reactivity with other proteins.
  • Application Supplier Note
    Tested Species: In-house tested species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.
  • Applications
    Flow Cytometry, ImmunoFluorescence, Western Blot, ImmunoHistoChemistry
  • Applications Supplier
    IHP, IHF, WB, IHC
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    500 ug/ml
  • Formulation
    Lyophilized
  • Gene ID12514
  • Target name
    Cd68
  • Target description
    CD68 antigen
  • Target synonyms
    gp11; gp110; La; Lamp4; ma; macrosialin; Sca; Scard1
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP31996
  • Protein Name
    Macrosialin
  • Scientific Description
    Superstar antibody: Bosters anti mouse CD68 antibody (PA1518) is among its top 10 bestselling antibodies, and one of the most cited mouse/rat CD68 antibodies on the market. Because of this antibodys high demand, we have subsequently developed a rabbit monoclonal anti CD68 antibody (M00602-1) targetting a similar epitope. High specificity: PA1518 reacts with murine macrosialin/CD68, and has been validated with Western blotting and confirmed its stellar specificity. CD68 is a highly glycosylated protein, and its expected western blot molecular weight is between 80kDa to 110kDa, depending on glycosylation level. PA1518s observed MW in WB is near 90-100kDa. Testing on negative control tissues showed no significant bands (images available on request) or staining. See more info in the positive and negative control design section. Based on immunogen sequence homology, this antibody is not expected to cross react with other proteins from the LAMP family, which complies with QC testing observations. Great for CD68 IHC: This antibody produces clean and specific immunobiological stains in both mouse and rat tissues. Our QC team has validated it on spleen and liver tissues of both mice and rats. Click product images for more details on experiment conditions. More about CD68: CD68 is a cell surface marker often used to identify macrophages and other cell types in the monocyte lineage. It is a transmembrane protein that binds to electins and selectins and plays a role in macrophage homing movement. Check out the CD68 biomarker page for more information on CD68 and view all CD68 antibodies, ELISA kits and proteins. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
  • Reactivity
    Hamster, Mouse, Rat
  • Reactivity Supplier
    Mouse, Rat, Hamster
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352203

References

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  • Chronic constant light exposure aggravates high fat diet-induced renal injury in rats. Xing L et al., 2022, Front Endocrinol (Lausanne)
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  • sTREM-1 promotes the phagocytic function of microglia to induce hippocampus damage via the PI3K-AKT signaling pathway. Lu L et al., 2022 Apr 29, Sci Rep
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  • Vancomycin Pretreatment on MPTP-Induced Parkinsons Disease Mice Exerts Neuroprotection by Suppressing Inflammation Both in Brain and Gut. Cui C et al., 2022 Jan 29, J Neuroimmune Pharmacol
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  • Procalcitonin is expressed in osteoblasts and limits bone resorption through inhibition of macrophage migration during intermittent PTH treatment. Baranowsky A et al., 2022 Jan 27, Bone Res
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  • Hypothermic oxygenated perfusion combined with TJ-M2010-5 alleviates hepatic ischemia-reperfusion injury in donation after circulatory death. Zhou W et al., 2022 Apr, Int Immunopharmacol
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  • A modified high-yield method for primary culture of rat retinal microglial cells. Han X et al., 2022 Feb, Exp Eye Res
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  • Human Exosomes Accelerate Cutaneous Wound Healing by Promoting Collagen Synthesis in a Diabetic Mouse Model. Zhao B et al., 2021 Sep 15, Stem Cells Dev
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  • Myeloid-derived growth factor inhibits inflammation and alleviates endothelial injury and atherosclerosis in mice. Meng B et al., 2021 May, Sci Adv
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  • The correlation between tumor-associated macrophage infiltration and progression in cervical carcinoma. Guo F et al., 2021 May 28, Biosci Rep
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