Anti-CD72 [BU40]

Absolute Antibody

Anti-CD72 [BU40]

7

This antibody has been used to investigate cell-surface expression of CD72 in FACS analysis (Kataoka et al, 2013). This antibody has been shown to induce resting B cells to enter the G1 phase of the cell cycle, stimulate B cell expression of major histocompatibility complex class II antigen and potentiate the capacity of IL-4 to induce CD23 production (Katira et al, 1992). It also stimulates TNF-alpha and IL-6 production in CD14+ monocytes (Yoshida et al, 2015). Ligation of CD72 by this antibody has been observed to suppress the proliferation of an acute myelogenous leukaemia cell line (Kataoka et al, 2013).

Flow Cytometry, Other Application

FC; stimulatory; activate

Research Use Only

Monoclonal

BU40

CD72

CD72 molecule

B-cell differentiation antigen CD72; CD72 antigen; CD72b; LYB2; lyb-2

Human

IgG1

B-cell differentiation antigen CD72

This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG2a format, for improved compatibility with existing reagents, assays and techniques.

Human

This antibody was raised against the HF B1 plasmacytoid cell line, which is considered to be late B-like.

-20°C,2°C to 8°C

12352203