Anti-CEACAM1 [B3-17]

Absolute Antibody

Anti-CEACAM1 [B3-17]

9

This antibody is specific for human CEACAM1, and recognises an epitope in the extracellular domain.

In flow cytometric analysis, this antibody has been used to detect CEACAM1 surface expression by human epithelial and endothelial cell lines, and microvesicles derived from these cells (Muturi et al, 2013), normal human bronchial epithelial (NHBE) cells (Klaile et al, 2013), CEACAM1-knockout human intestinal epithelial cells (Klaile et al, 2017) and human B-cell subpopulations (Khairnar et al, 2015; Seifert et al, 2015). It has also been used to detect CEACAM1 expression in ELISA analysis of transfected A549 epithelial cells (Singer et al, 2014). This antibody has been used in immunofluorescence analysis of NHBE cells (Klaile et al, 2013), as well as in the immunoprecipitation of CEACAM1 from NHBE cell culture supernatants (Klaile et al, 2013). Additionally, this antibody has been used in IHC staining of paraffin-embedded human lung tissue sections (Klaile et al, 2013).

Flow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, ELISA, ImmunoHistoChemistry

Research Use Only

Monoclonal

B3-17

CEACAM1

CEA cell adhesion molecule 1

antigen CD66; BGP; BGP1; BGPI; carcinoembryonic antigen related cell adhesion molecule 1; carcinoembryonic antigen-related cell adhesion molecule 1; carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein); CD66a antigen

Human

IgG1

Carcinoembryonic antigen-related cell adhesion molecule 1

This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.

Human

-20°C,2°C to 8°C

12352203