Anti-Cyclin B1 Antibody
R1308-13
ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse
TargetCCNB1
Overview
- SupplierHUABIO
- Product NameAnti-Cyclin B1 Antibody
- Delivery Days Customer7
- ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- Applications SupplierWB,IF-Cell,IHC-P,FC
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID891
- Target nameCCNB1
- Target descriptioncyclin B1
- Target synonymsCCNB, G2/mitotic-specific cyclin-B1
- HostRabbit
- IsotypeIgG
- Protein IDP14635
- Protein NameG2/mitotic-specific cyclin-B1
- Scientific DescriptionCyclins are a family of proteins that activate specific cyclin-dependent kinases required for progression through the cell cycle. The entry of all eukaryotic cells into mitosis is regulated by activation of cdc2/cdk1 at the G2/M transition. Cyclin B1 is essential for the control of the cell cycle at the G2/M (mitosis) transition. It interacts with the CDC2 protein kinase to form a serine/threonine kinase holoenzyme complex also known as maturation promoting factor (MPF). The cyclin subunit imparts substrate specificity to the complex. Four cyclin B1 phosphorylation sites (Ser126, 128, 133, and 147) are located in the cytoplasmic retention signal (CRS) domain and are thought to regulate the translocation of cyclin B1 to the nucleus at the G2/M checkpoint, promoting nuclear accumulation and initiation of mitosis.
- ReactivityHuman, Mouse
- Reactivity SupplierHuman,Mouse
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC41116161






