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Immunohistochemical staining of formalin fixed and paraffin embedded human heart tissue sections using Anti-Desmin RM234 at a 1:4000 dilution.
Immunohistochemical staining of formalin fixed and paraffin embedded human heart tissue sections using Anti-Desmin RM234 at a 1:4000 dilution.
Immunohistochemical staining of formalin fixed and paraffin embedded human heart tissue sections using Anti-Desmin RM234 at a 1:4000 dilution.

anti-Desmin, Rabbit Monoclonal (RM234)

Research Use Only
REV-31-1124-00
RevMAb Biosciences
ApplicationsWestern Blot, ImmunoHistoChemistry
DownloadDatasheet
Product group Antibodies
ReactivityHuman, Mouse
TargetDES
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Overview

  • Supplier
    RevMAb Biosciences
  • Product Name
    anti-Desmin, Rabbit Monoclonal (RM234)
  • Delivery Days Customer
    5
  • Antibody Specificity
    This antibody reacts to human and mouse Desmin. This antibody may also react to rat and Bovine Desmin, as predicted by immunogen homology.
  • Applications
    Western Blot, ImmunoHistoChemistry
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    RM234
  • Formulation
    Liquid
  • Gene ID1674
  • Target name
    DES
  • Target description
    desmin
  • Target synonyms
    cardiomyopathy, dilated 1F (autosomal dominant); CDCD3; CSM1; CSM2; desmin; epididymis secretory sperm binding protein; intermediate filament protein; LGMD1D; LGMD1E; LGMD2R
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP17661
  • Protein Name
    Desmin
  • Scientific Description
    Desmin (approximately 53 kDa) exhibits a high degree of tissue specificity, its expression being predominantly confined to all types of muscle cells (cardiac, skeletal and smooth muscle). Regulation of desmin expression is stage and tissue-specific, since it is induced during terminal development of, for example, skeletal muscle cell differentiation. In skeletal en cardiac muscle cells desmin is localized in the Z-disk region and at the intercalated disk. The expression pattern of desmin in smooth muscle is much more heterogenous. Coexpression of vimentin and desmin has been observed in tumors derived from muscle tissue. Desmin (DES) mutations have been associated with restrictive, dilated, idiopathic, arrhythmogenic and non-compaction cardimyopathy. - Recombinant Antibody. This antibody reacts to human and mouse Desmin. This antibody may also react to rat and Bovine Desmin, as predicted by immunogen homology. Applications: WB, IHC. Source: Rabbit. Liquid. 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide. Desmin (approximately 53 kDa) exhibits a high degree of tissue specificity, its expression being predominantly confined to all types of muscle cells (cardiac, skeletal and smooth muscle). Regulation of desmin expression is stage and tissue-specific, since it is induced during terminal development of, for example, skeletal muscle cell differentiation. In skeletal en cardiac muscle cells desmin is localized in the Z-disk region and at the intercalated disk. The expression pattern of desmin in smooth muscle is much more heterogenous. Coexpression of vimentin and desmin has been observed in tumors derived from muscle tissue. Desmin (DES) mutations have been associated with restrictive, dilated, idiopathic, arrhythmogenic and non-compaction cardimyopathy.
  • Reactivity
    Human, Mouse
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352203