anti-EVI1 / AML1 antibody
ARG65147
ApplicationsWestern Blot
Product group Antibodies
ReactivityHuman
TargetMECOM
Overview
- SupplierArigo Biolaboratories
- Product Nameanti-EVI1 / AML1 antibody
- Delivery Days Customer23
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.5 mg/ml
- ConjugateUnconjugated
- Gene ID2122
- Target nameMECOM
- Target descriptionMDS1 and EVI1 complex locus
- Target synonymsAML1-EVI-1; AML1-EVI-1 fusion protein; ecotropic virus integration site 1 protein homolog; EVI1; histone-lysine N-methyltransferase MECOM; KMT8E; MDS1; MDS1 and EVI1 complex locus protein EVI1; MDS1 and EVI1 complex locus protein MDS1; MDS1-EVI1; myelodysplasia syndrome-associated protein 1; oncogene EVI1; PR domain 3; PRDM3; RUSAT2; zinc finger protein Evi1
- HostGoat
- IsotypeIgG
- Scientific DescriptionThe protein encoded by this gene is a transcriptional regulator and oncoprotein that may be involved in hematopoiesis, apoptosis, development, and cell differentiation and proliferation. The encoded protein can interact with CTBP1, SMAD3, CREBBP, KAT2B, MAPK8, and MAPK9. This gene can undergo translocation with the AML1 gene, resulting in overexpression of this gene and the onset of leukemia. Several transcript variants encoding a few different isoforms have been found for this gene. [provided by RefSeq, Mar 2011]
- ReactivityHuman
- Storage Instruction-20°C
- UNSPSC12352203