Immunohistochemical staining of formalin fixed and paraffin embedded human Glioblastoma Multiforme tissue sections with or without EGFRvIIII using anti-EGFRvIII antibody (RM419) at 1:100 dilution.
Immunohistochemical staining of formalin fixed and paraffin embedded human Glioblastoma Multiforme tissue sections with or without EGFRvIIII using anti-EGFRvIII antibody (RM419) at 1:100 dilution.
anti-Foxp1 (human), Rabbit Monoclonal (RM402)
REV-31-1288-00
ApplicationsWestern Blot, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetFOXP1
Overview
- SupplierRevMAb Biosciences
- Product Nameanti-Foxp1 (human), Rabbit Monoclonal (RM402)
- Delivery Days Customer5
- Antibody SpecificityThis antibody reacts to human to Foxp1.
- ApplicationsWestern Blot, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDRM402
- FormulationLiquid
- Gene ID27086
- Target nameFOXP1
- Target descriptionforkhead box P1
- Target synonyms12CC4; fork head-related protein like B; forkhead box protein P1; glutamine-rich factor 1; hFKH1B; HSPC215; mac-1-regulated forkhead; MFH; QRF1
- HostRabbit
- IsotypeIgG
- Protein IDQ9H334
- Protein NameForkhead box protein P1
- Scientific DescriptionFoxp1 (Forkhead box P1) belongs to subfamily P of the forkhead box (FOX) transcription factor family. Forkhead box transcription factors play important roles in the regulation of tissue- and cell type-specific gene transcription during both development and adulthood. The Foxp1 protein contains both DNA-binding- and protein-protein binding-domains. This protein may act as a tumor suppressor as it is lost in several tumor types. Foxp1 regulates a variety of important aspects of development including tissue development of the lungs, brain, thymus and heart. In the heart Foxp1 has 3 vital roles, these include the regulation of cardiac myocyte maturation and proliferation, outflow tract separation of the pulmonary artery and aorta and expression of Sox4 in cushions and myocardium. Foxp1 is also an important regulator of lung airway morphogenesis. Foxp1 knockout embryos display severe defects in cardiac morphogenesis. Disruptions of FoxP1 have been identified in very rare human patients and lead to cognitive dysfunction, including intellectual disability and autism spectrum disorder, together with language impairment. - Recombinant Antibody. This antibody reacts to human to Foxp1. Applications: WB, IHC. Source: Rabbit. Liquid. 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide. Foxp1 (Forkhead box P1) belongs to subfamily P of the forkhead box (FOX) transcription factor family. Forkhead box transcription factors play important roles in the regulation of tissue- and cell type-specific gene transcription during both development and adulthood. The Foxp1 protein contains both DNA-binding- and protein-protein binding-domains. This protein may act as a tumor suppressor as it is lost in several tumor types. Foxp1 regulates a variety of important aspects of development including tissue development of the lungs, brain, thymus and heart. In the heart Foxp1 has 3 vital roles, these include the regulation of cardiac myocyte maturation and proliferation, outflow tract separation of the pulmonary artery and aorta and expression of Sox4 in cushions and myocardium. Foxp1 is also an important regulator of lung airway morphogenesis. Foxp1 knockout embryos display severe defects in cardiac morphogenesis. Disruptions of FoxP1 have been identified in very rare human patients and lead to cognitive dysfunction, including intellectual disability and autism spectrum disorder, together with language impairment.
- ReactivityHuman
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352203