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anti-FOXP3 (human), mAb (ANCFX2D7) (R-PE)

Research Use Only
ANC-333-050
Ancell Corporation
ApplicationsFlow Cytometry, ELISA
Product group Antibodies
ReactivityHuman
Price on request
Packing Size
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Overview

  • Supplier
    Ancell Corporation
  • Product Name
    anti-FOXP3 (human), mAb (ANCFX2D7) (R-PE)
  • Delivery Days Customer
    10
  • Antibody Specificity
    Recognizes human FOXP3.
  • Applications
    Flow Cytometry, ELISA
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    ANCFX2D7
  • Conjugate
    RPE
  • Estimated Purity
    >95%
  • Host
    Mouse
  • Isotype
    IgG1
  • Scientific Description
    FOXP3 is involved in immune system responses. It functions as the master regulator in the development and function of regulatory T cells. FOX proteins belong to the forkhead/winged-helix family of transcriptional regulators and are presumed to exert control via similar DNA binding interactions during transcription. Defects in FOXP3 are the cause of immunodeficiency polyendocrinopathy, enteropathy, X-linked syndrome (IPEX); also known as X-linked autoimmunity-immunodeficiency syndrome. IPEX is characterized by neonatal onset insulin-dependent diabetes mellitus, infections, secretory diarrhea, trombocytopenia, anemia and eczema. - Monoclonal Antibody. Recognizes human FOXP3. Isotype: Mouse IgG1kappa. Clone: ANCFX2D7. Application: ELISA, FACS. 50mM Sodium phosphate pH7.5, 500mM Potassium chloride, 150mM NaCl, 15% glycerol, 0.2%BSA, 0.04% sodium azide (as preservative). FOXP3 is involved in immune system responses. It functions as the master regulator in the development and function of regulatory T cells. FOX proteins belong to the forkhead/winged-helix family of transcriptional regulators and are presumed to exert control via similar DNA binding interactions during transcription. Defects in FOXP3 are the cause of immunodeficiency polyendocrinopathy, enteropathy, X-linked syndrome (IPEX); also known as X-linked autoimmunity-immunodeficiency syndrome. IPEX is characterized by neonatal onset insulin-dependent diabetes mellitus, infections, secretory diarrhea, trombocytopenia, anemia and eczema.
  • Reactivity
    Human
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203