anti-FOXP3 (human), mAb (ANCFX2D7) (R-PE)
ANC-333-050
ApplicationsFlow Cytometry, ELISA
Product group Antibodies
ReactivityHuman
Overview
- SupplierAncell Corporation
- Product Nameanti-FOXP3 (human), mAb (ANCFX2D7) (R-PE)
- Delivery Days Customer10
- Antibody SpecificityRecognizes human FOXP3.
- ApplicationsFlow Cytometry, ELISA
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDANCFX2D7
- ConjugateRPE
- Estimated Purity>95%
- HostMouse
- IsotypeIgG1
- Scientific DescriptionFOXP3 is involved in immune system responses. It functions as the master regulator in the development and function of regulatory T cells. FOX proteins belong to the forkhead/winged-helix family of transcriptional regulators and are presumed to exert control via similar DNA binding interactions during transcription. Defects in FOXP3 are the cause of immunodeficiency polyendocrinopathy, enteropathy, X-linked syndrome (IPEX); also known as X-linked autoimmunity-immunodeficiency syndrome. IPEX is characterized by neonatal onset insulin-dependent diabetes mellitus, infections, secretory diarrhea, trombocytopenia, anemia and eczema. - Monoclonal Antibody. Recognizes human FOXP3. Isotype: Mouse IgG1kappa. Clone: ANCFX2D7. Application: ELISA, FACS. 50mM Sodium phosphate pH7.5, 500mM Potassium chloride, 150mM NaCl, 15% glycerol, 0.2%BSA, 0.04% sodium azide (as preservative). FOXP3 is involved in immune system responses. It functions as the master regulator in the development and function of regulatory T cells. FOX proteins belong to the forkhead/winged-helix family of transcriptional regulators and are presumed to exert control via similar DNA binding interactions during transcription. Defects in FOXP3 are the cause of immunodeficiency polyendocrinopathy, enteropathy, X-linked syndrome (IPEX); also known as X-linked autoimmunity-immunodeficiency syndrome. IPEX is characterized by neonatal onset insulin-dependent diabetes mellitus, infections, secretory diarrhea, trombocytopenia, anemia and eczema.
- ReactivityHuman
- Storage Instruction2°C to 8°C
- UNSPSC12352203