anti-FOXP3 (mouse), mAb (MF333F)

AdipoGen Life Sciences

anti-FOXP3 (mouse), mAb (MF333F)

10

Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry

Research Use Only

Monoclonal

MF333F

1 mg/ml

>95%

Foxp3

forkhead box P3

JM2, scurfin, sf, forkhead box protein P3, scurfy

Rat

IgG2a

Forkhead box protein P3

FOXP3 is involved in immune system responses. It functions as the master regulator in the development and function of regulatory T cells. FOX proteins belong to the forkhead/winged-helix family of transcriptional regulators and are presumed to exert control via similar DNA binding interactions during transcription. Defects in FOXP3 are the cause of immunodeficiency polyendocrinopathy, enteropathy, X-linked syndrome (IPEX); also known as X-linked autoimmunity-immunodeficiency syndrome. IPEX is characterized by neonatal onset insulin-dependent diabetes mellitus, infections, secretory diarrhea, trombocytopenia, anemia and eczema. - Monoclonal Antibody. Recognizes mouse FOXP3. Detects a band of ~46-49kDa by Western blot. Isotype: Rat IgG2akappa. Clone: MF333F. Applications: ELISA, ICC, IHC, WB. Liquid. 0.2microm-filtered solution in PBS, pH 7.4. Contains no preservatives. FOXP3 is involved in immune system responses. It functions as the master regulator in the development and function of regulatory T cells. FOX proteins belong to the forkhead/winged-helix family of transcriptional regulators and are presumed to exert control via similar DNA binding interactions during transcription. Defects in FOXP3 are the cause of immunodeficiency polyendocrinopathy, enteropathy, X-linked syndrome (IPEX); also known as X-linked autoimmunity-immunodeficiency syndrome. IPEX is characterized by neonatal onset insulin-dependent diabetes mellitus, infections, secretory diarrhea, trombocytopenia, anemia and eczema.

Mouse

-20°C,2°C to 8°C

41116161