anti-HMGB1 Neutralizing antibody [SQab20175] (low endotoxin)

Arigo Biolaboratories

anti-HMGB1 Neutralizing antibody [SQab20175] (low endotoxin)

23

Neutralizing assay: ARG66714 anti-HMGB1 Neutralizing antibody [SQab20175] suppresses HMGB1 induced TNF alpha releasing in both THP1 and Raw264.7 cell model. Please refer the data at below. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Flow Cytometry, Western Blot, ELISA, Neutralisation/Blocking

Research Use Only

Monoclonal

SQab20175

0.5 mg/ml

Unconjugated

HMGB1

high mobility group box 1

HMG-1, HMG1, HMG3, SBP-1, high mobility group protein B1, Amphoterin, Sulfoglucuronyl carbohydrate binding protein, high-mobility group (nonhistone chromosomal) protein 1

Mouse

IgM

High mobility group protein B1

HMGB1 is a protein that belongs to the High Mobility Group-box superfamily. The encoded non-histone, nuclear DNA-binding protein regulates transcription, and is involved in organization of DNA. This protein plays a role in several cellular processes, including inflammation, cell differentiation and tumor cell migration. Multiple pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Sep 2015]

Human

2°C to 8°C or -20°C

41116161