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Western blot analysis using anti-IL-33 (human), mAb (IL33068A) (Prod. No. AG-20A-0042) at 1:2000 dilution.1: Human IL-33 (His-tagged).2: Human IL-33 (FLAG®-tagged).3: Mouse IL-33 (FLAG®-tagged).4: Other prote
Western blot analysis using anti-IL-33 (human), mAb (IL33068A) (Prod. No. AG-20A-0042) at 1:2000 dilution.1: Human IL-33 (His-tagged).2: Human IL-33 (FLAG®-tagged).3: Mouse IL-33 (FLAG®-tagged).4: Other prote
Western blot analysis using anti-IL-33 (human), mAb (IL33068A) (Prod. No. AG-20A-0042) at 1:2000 dilution.1: Human IL-33 (His-tagged).2: Human IL-33 (FLAG®-tagged).3: Mouse IL-33 (FLAG®-tagged).4: Other prote

anti-IL-33, mAb (IL33068A)

Research Use Only
AG-20A-0042
AdipoGen Life Sciences
ApplicationsWestern Blot, ELISA
Product group Antibodies
ReactivityHuman
TargetIL33
Price on request
Packing Size
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    AdipoGen Life Sciences
  • Product Name
    anti-IL-33, mAb (IL33068A)
  • Delivery Days Customer
    10
  • Antibody Specificity
    Recognizes human IL-33. Weakly cross-reacts with mouse IL-33.
  • Applications
    Western Blot, ELISA
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    IL33068A
  • Concentration
    1 mg/ml
  • Formulation
    Liquid
  • Gene ID90865
  • Target name
    IL33
  • Target description
    interleukin 33
  • Target synonyms
    C9orf26; DVS27; DVS27-related protein; IL1F11; interleukin-1 family member 11; interleukin-33; NFEHEV; NF-HEV; nuclear factor for high endothelial venules; nuclear factor from high endothelial venules
  • Host
    Mouse
  • Isotype
    IgG2b
  • Protein IDO95760
  • Protein Name
    Interleukin-33
  • Scientific Description
    Interleukin-33 (IL-33; HF-NEV; IL-1F11), a member of the IL-1 family of cytokines, is expressed by many cell types following pro-inflammatory stimulation and is thought to be released on cell lysis. The 30kDa human IL33 is converted by CASP1 to a 18kDa protein. IL33 binds to and signals through ST2 (IL1R1) and its stimulation recruits MYD88, IRAK, IRAK4, and TRAF6, followed by phosphorylation of ERK1(MAPK3)/ERK2(MAPK1), p38(MAPK14), and JNK. The ability of IL-33 to target numerous immune cell types, like Th2-like cells, mast cells, and B1 cells, and to induce cytokine and chemokine production underlines its potential in influencing the outcome of a wide range of diseases, such as arthritis, asthma, atopic allergy & anaphylaxis, cardiovascular disease/atherosclerosis, nervous system diseases, and sepsis. - Monoclonal Antibody. Recognizes human IL-33. Weakly cross-reacts with mouse IL-33. Isotype: Mouse IgG2bkappa. Clone: IL33068A. Applications: ELISA, WB. Liquid. 0.2microm-filtered solution in PBS, pH 7.4. Contains no preservatives. Interleukin-33 (IL-33; HF-NEV; IL-1F11), a member of the IL-1 family of cytokines, is expressed by many cell types following pro-inflammatory stimulation and is thought to be released on cell lysis. The 30kDa human IL33 is converted by CASP1 to a 18kDa protein. IL33 binds to and signals through ST2 (IL1R1) and its stimulation recruits MYD88, IRAK, IRAK4, and TRAF6, followed by phosphorylation of ERK1(MAPK3)/ERK2(MAPK1), p38(MAPK14), and JNK. The ability of IL-33 to target numerous immune cell types, like Th2-like cells, mast cells, and B1 cells, and to induce cytokine and chemokine production underlines its potential in influencing the outcome of a wide range of diseases, such as arthritis, asthma, atopic allergy & anaphylaxis, cardiovascular disease/atherosclerosis, nervous system diseases, and sepsis.
  • Reactivity
    Human
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352203