Anti-IL-8 [6G4.2.5V11N35A]

Absolute Antibody

Anti-IL-8 [6G4.2.5V11N35A]

9

This antibody binds human IL-8, which is a chemotactic factor that attracts neutrophils, basophils, and T-cells, but not monocytes. It is also involved in neutrophil activation. It is released from several cell types in response to an inflammatory stimulu

This antibody is capable of neutralizing the biological activity of wild-type human IL-8. This antibody is reported to inhibit human wild type IL-8, human monomeric IL-8, rabbit IL-8, and rhesus IL-8 mediated neutrophil chemotaxis (US6025158). The binding characterization of this antibody was done using ELISA. The Fab version of this antibody binds human IL-8 with an affinity of 114 pM (US6025158).

ELISA, Neutralisation/Blocking

Research Use Only

Monoclonal

6G4.2.5V11N35A

CXCL8

C-X-C motif chemokine ligand 8

alveolar macrophage chemotactic factor I; beta endothelial cell-derived neutrophil activating peptide; beta-thromboglobulin-like protein; chemokine (C-X-C motif) ligand 8; emoctakin; GCP1; GCP-1; granulocyte chemotactic protein 1; IL8; interleukin 8; interleukin-8; LECT; LUCT; lung giant cell carcinoma-derived chemotactic protein; lymphocyte derived neutrophil activating peptide; LYNAP; MDNCF; MONAP; monocyte-derived neutrophil chemotactic factor; monocyte-derived neutrophil-activating peptide; NAF; NAP1; NAP-1; neutrophil-activating peptide 1; SCYB8; small inducible cytokine subfamily B, member 8; T-cell chemotactic factor; tumor necrosis factor-induced gene 1

Human

Interleukin-8

This reformatted human antibody was made using the variable domain sequences of the original Human IgG1 format for improved compatibility with existing reagents assays and techniques.

Human, Primate, Rabbit

-20°C,2°C to 8°C

12352203