Immunohistochemical staining of formalin fixed and paraffin embedded human kidney tissue sections using Anti-JAM1 Rabbit Monoclonal Antibody (Clone RM275) at a 1:10000 dilution.
Immunohistochemical staining of formalin fixed and paraffin embedded human kidney tissue sections using Anti-JAM1 Rabbit Monoclonal Antibody (Clone RM275) at a 1:10000 dilution.
anti-JAM1 (human), Rabbit Monoclonal (RM275)
REV-31-1156-00
ApplicationsWestern Blot, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetF11R
Overview
- SupplierRevMAb Biosciences
- Product Nameanti-JAM1 (human), Rabbit Monoclonal (RM275)
- Delivery Days Customer5
- ApplicationsWestern Blot, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDRM275
- Gene ID50848
- Target nameF11R
- Target descriptionF11 receptor
- Target synonymsCD321; JAM; JAM1; JAMA; JCAM; junctional adhesion molecule 1; junctional adhesion molecule A; KAT; PAM-1; platelet adhesion molecule 1; platelet F11 receptor
- HostRabbit
- IsotypeIgG
- Scientific DescriptionJAM-1 (CD321; F11R; JAM-A) is a cell-surface adhesion molecule belonging to the Ig superfamily of receptors. JAM-1 is a 32-41 kD glycoprotein, possessing two extracellular Ig-like domains, a transmembrane region, and a short cytosolic tail. The protein assembles at the membrane as a homodimer, and can associate laterally with other membrane proteins including integrins. JAM-1 is expressed on a variety of cell types, including leukocytes, platelets, erythrocytes, stem cells, epithelial and endothelial cells, and plays a role in mediating cell-cell contact. JAM-1 can be found in close proximity to several components of epithelial tight junctions, including ZO-1 and occludin. JAM-1 is involved in the maintenance of epithelial and endothelial barriers, hematopoiesis, angiogenesis, and tumor proliferation, invasion and metastasis. - Recombinant Antibody. This antibody reacts to human JAM1 (Junctional adhesion molecule 1). Applications: WB, IHC. Source: Rabbit. Liquid. 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide. JAM-1 (CD321; F11R; JAM-A) is a cell-surface adhesion molecule belonging to the Ig superfamily of receptors. JAM-1 is a 32-41 kD glycoprotein, possessing two extracellular Ig-like domains, a transmembrane region, and a short cytosolic tail. The protein assembles at the membrane as a homodimer, and can associate laterally with other membrane proteins including integrins. JAM-1 is expressed on a variety of cell types, including leukocytes, platelets, erythrocytes, stem cells, epithelial and endothelial cells, and plays a role in mediating cell-cell contact. JAM-1 can be found in close proximity to several components of epithelial tight junctions, including ZO-1 and occludin. JAM-1 is involved in the maintenance of epithelial and endothelial barriers, hematopoiesis, angiogenesis, and tumor proliferation, invasion and metastasis.
- ReactivityHuman
- Storage Instruction-20°C
- UNSPSC12352203