Bio-Connect

Anti-mSin3A Antibody

ER2001-38
HUABIO
ApplicationsWestern Blot
Product group Antibodies
ReactivityHuman
TargetSIN3A
100 ul
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Overview

  • Supplier
    HUABIO
  • Product Name
    Anti-mSin3A Antibody
  • Delivery Days Customer
    7
  • Applications
    Western Blot
  • Applications Supplier
    WB
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID25942
  • Target name
    SIN3A
  • Target description
    SIN3 transcription regulator family member A
  • Target synonyms
    CHR15DELq24, DEL15Q24, WITKOS, paired amphipathic helix protein Sin3a, SIN3 homolog A, transcription regulator, histone deacetylase complex subunit Sin3a, transcriptional co-repressor Sin3A, transcriptional corepressor Sin3a, transcriptional regulator, SIN3A
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ96ST3
  • Protein Name
    Paired amphipathic helix protein Sin3a
  • Scientific Description
    Acts as a transcriptional repressor. Corepressor for REST. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Also interacts with MXD1-MAX heterodimers to repress transcription by tethering SIN3A to DNA. Acts cooperatively with OGT to repress transcription in parallel with histone deacetylation. Involved in the control of the circadian rhythms. Required for the transcriptional repression of circadian target genes, such as PER1, mediated by the large PER complex through histone deacetylation. Cooperates with FOXK1 to regulate cell cycle progression probably by repressing cell cycle inhibitor genes expression (By similarity). Required for cortical neuron differentiation and callosal axon elongation (By similarity).
  • Reactivity
    Human
  • Reactivity Supplier
    Human
  • Reactivity Supplier Note
    Mouse,Rat
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    41116161