Western blot analysis using anti-Nampt (human), pAb (Prod. No. AG-25A-0025B) at 1:2000 dilution. 1: Human Nampt (His-tagged). 2: LPS-treated human peripheral blood leukocyte lysate.
Western blot analysis using anti-Nampt (human), pAb (Prod. No. AG-25A-0025B) at 1:2000 dilution. 1: Human Nampt (His-tagged). 2: LPS-treated human peripheral blood leukocyte lysate.
anti-Nampt (Visfatin/PBEF) (human), pAb (Biotin)
AG-25A-0025B
ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetNAMPT
Overview
- SupplierAdipoGen Life Sciences
- Product Nameanti-Nampt (Visfatin/PBEF) (human), pAb (Biotin)
- Delivery Days Customer10
- Antibody SpecificityRecognizes human Nampt. Weakly cross-reacts with mouse Nampt. Detects a band of ~54kDa by Western blot.
- ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateBiotin
- FormulationLiquid
- Gene ID10135
- Target nameNAMPT
- Target descriptionnicotinamide phosphoribosyltransferase
- Target synonyms1110035O14Rik; NAmPRTase; nicotinamide phosphoribosyltransferase; PBEF; PBEF1; pre-B cell-enhancing factor; pre-B-cell colony-enhancing factor 1; VF; VISFATIN
- HostRabbit
- Protein IDP43490
- Protein NameNicotinamide phosphoribosyltransferase
- Scientific DescriptionNicotinamide phosphoribosyltransferase (Nampt; pre-B cell colony-enhancing factor; PBEF; Visfatin) is an 52kDa adipokine secreted by adipose tissue and involved in the biosynthesis of nicotinamide adenine dinucleotide (NAD+). Two forms of Nampt exist, an intracellular form (iNampt) and an extracellular form (eNampt). While the function of iNampt as an essential and rate-limiting NAD+ biosynthetic enzyme is well established, the physiological role of eNampt is still a matter of debate. Nampt has various functions, including the promotion of vascular smooth muscle cell maturation and inhibition of neutrophil apoptosis. It activates insulin receptor and has insulin-mimetic effects, lowering blood glucose and improving insulin sensitivity. The protein is highly expressed in visceral fat and serum levels of the protein correlate with obesity. - Polyclonal Antibody. Recognizes human Nampt. Weakly cross-reacts with mouse Nampt. Detects a band of ~54kDa by Western blot. Source: Rabbit. Applications: ELISA, IHC, WB. Liquid. 0.2microm-filtered solution in PBS, pH 7.4. Contains no preservatives. Nicotinamide phosphoribosyltransferase (Nampt; pre-B cell colony-enhancing factor; PBEF; Visfatin) is an 52kDa adipokine secreted by adipose tissue and involved in the biosynthesis of nicotinamide adenine dinucleotide (NAD+). Two forms of Nampt exist, an intracellular form (iNampt) and an extracellular form (eNampt). While the function of iNampt as an essential and rate-limiting NAD+ biosynthetic enzyme is well established, the physiological role of eNampt is still a matter of debate. Nampt has various functions, including the promotion of vascular smooth muscle cell maturation and inhibition of neutrophil apoptosis. It activates insulin receptor and has insulin-mimetic effects, lowering blood glucose and improving insulin sensitivity. The protein is highly expressed in visceral fat and serum levels of the protein correlate with obesity.
- ReactivityHuman
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352203