Anti-NKG2D [ON72]

Absolute Antibody

Anti-NKG2D [ON72]

9

This antibody recognizes human, cynomolgous monkey and rhesus monkey NKG2D, but does not cross react with mouse rat, dog or pig NKG2D. Natural killer (NK) cells serve as key innate effectors and their activity has been considered a prognostic biomarker in

This antibody is capable of recognizing NKG2D in an ELISA. This antibody was successful in staining and identification NKG2D expressed on PBMCs isolated from human, cynomolgous monkey and rhesus monkey in a flow cytometric assay (US7879985). This antibody was used to study the distribution of NKG2D on human peripheral blood cells by flow cytometry (PMID: 15048706). The immobilized version of this antibody was reported to show agonistic activity (US7879985).

Flow Cytometry, ELISA, Other Application

Research Use Only

Monoclonal

ON72

KLRK1

killer cell lectin like receptor K1

CD314; D12S2489E; killer cell lectin-like receptor subfamily K, member 1; KLR; NK cell receptor D; NKG2D; NKG2-D; NKG2-D type II integral membrane protein; NKG2-D-activating NK receptor

Mouse

IgG2b

NKG2-D type II integral membrane protein

This chimeric mouse antibody was made using the variable domain sequences of the original Human IgG1 format for improved compatibility with existing reagents assays and techniques.

Human, Monkey, Primate

-20°C,2°C to 8°C

12352203