Anti-p53 Antibody
R1308-7
ApplicationsImmunoFluorescence, Western Blot
Product group Antibodies
ReactivityHuman
TargetTP53
Overview
- SupplierHUABIO
- Product NameAnti-p53 Antibody
- Delivery Days Customer7
- ApplicationsImmunoFluorescence, Western Blot
- Applications SupplierWB,IF-Cell
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID7157
- Target nameTP53
- Target descriptiontumor protein p53
- Target synonymsBCC7, BMFS5, LFS1, P53, TRP53, cellular tumor antigen p53, antigen NY-CO-13, mutant tumor protein 53, phosphoprotein p53, transformation-related protein 53, tumor protein 53, tumor supressor p53
- HostRabbit
- IsotypeIgG
- Protein IDP04637
- Protein NameCellular tumor antigen p53
- Scientific DescriptionThe p53 tumor suppressor protein plays a major role in cellular response to DNA damage and other genomic aberrations. Activation of p53 can lead to either cell cycle arrest and DNA repair or apoptosis. It is involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. p53 is phosphorylated at multiple sites in vivo and by several different protein kinases in vitro. P53 is found in increased amounts in a wide variety of transformed cells. P53 is frequently mutated or inactivated in about 60% of cancers.
- ReactivityHuman
- Reactivity SupplierHuman
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC41116161








