anti-p70S6K (human), Rabbit Monoclonal (RM438)

RevMAb Biosciences

anti-p70S6K (human), Rabbit Monoclonal (RM438)

10

Western Blot, ImmunoHistoChemistry

Research Use Only

Monoclonal

RM438

RPS6KB1

ribosomal protein S6 kinase B1

p70 S6KA; p70(S6K)-alpha; p70-alpha; p70-S6K; PS6K; ribosomal protein S6 kinase beta-1; ribosomal protein S6 kinase I; ribosomal protein S6 kinase, 70kDa, polypeptide 1; S6K; S6K1; S6K-beta-1; serine/threonine kinase 14 alpha; serine/threonine-protein kinase 14A; STK14A

Rabbit

IgG

Ribosomal protein S6 kinase beta-1

Recombinant Antibody. This antibody reacts to human p70S6K. Apllication: IHC, WB. Liquid. 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide. The p70S6 kinase (p70 Ribosomal Protein S6 Kinase, p70S6K) is a 70kDa member of the ribosomal S6 kinase (RSK) family of serine/threonine kinases. p70S6 kinase is predominantly localized in the cytoplasm and is essential in growth factors regulated cell proliferation, pathways involving cell motility, such as metastases, the immune response and tissue repair. p70S6 kinase acts downstream of phosphoinositide (PI) 3-kinase and its main physiological target is the S6 ribosomal protein, which is involved in upregulation of protein synthesis. The kinase activity of p70S6 kinase leads to an increase in protein synthesis and cell proliferation. Amplification of the region of DNA encoding p70S6 kinase and overexpression are seen in some breast cancer cell lines. - The p70S6 kinase (p70 Ribosomal Protein S6 Kinase, p70S6K) is a 70kDa member of the ribosomal S6 kinase (RSK) family of serine/threonine kinases. p70S6 kinase is predominantly localized in the cytoplasm and is essential in growth factors regulated cell proliferation, pathways involving cell motility, such as metastases, the immune response and tissue repair. p70S6 kinase acts downstream of phosphoinositide (PI) 3-kinase and its main physiological target is the S6 ribosomal protein, which is involved in upregulation of protein synthesis. The kinase activity of p70S6 kinase leads to an increase in protein synthesis and cell proliferation. Amplification of the region of DNA encoding p70S6 kinase and overexpression are seen in some breast cancer cell lines.

-20°C

12352203