Anti-Paxillin (LD4 Motif) [LD4 sAB]

Absolute Antibody

Anti-Paxillin (LD4 Motif) [LD4 sAB]

9

The antibody binds specifically to the LD-4 motif of human paxillin with a Kd of 6 nM.

This antibody binds to the LD4-motif of human paxillin, a signal transduction adaptor protein involved in focal adhesion, with binding partners including integrins, Src, FAK or actin complexes. The antibody inhibits complex formation between paxillin and FAK. Paxillin is involved in both inside-out cell signalling and outside-to-inside cell signalling.

Western Blot, ELISA

Research Use Only

Monoclonal

LD4 sAB

PXN

paxillin

paxillin; testicular tissue protein Li 134

Rabbit

IgG

Paxillin

This full-length, chimeric rabbit antibody was made using the variable domain sequences of the original Mouse scFv format, for improved compatibility with existing reagents, assays and techniques.

Human

-20°C,2°C to 8°C

12352203