Western blot: HeLa, SP2/0 and H9C2 cells. These cells treated with H2O2 and stained with ARG66579 anti-PFKFB2 phospho (Ser483) antibody.
Western blot: HeLa, SP2/0 and H9C2 cells. These cells treated with H2O2 and stained with ARG66579 anti-PFKFB2 phospho (Ser483) antibody.
anti-PFKFB2 phospho (Ser483) antibody
ARG66579
TargetPFKFB2
Product group Antibodies
Overview
- SupplierArigo Biolaboratories
- Product Nameanti-PFKFB2 phospho (Ser483) antibody
- Delivery Days Customer23
- Gene ID5208
- Target namePFKFB2
- Target description6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
- Target synonyms6PF-2-K/Fru-2,6-P2ase 2; 6PF-2-K/Fru-2,6-P2ASE heart-type isozyme; 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2; fructose-2,6-bisphosphatase, cardiac isozyme; PFK/FBPase 2; PFK-2/FBPase-2; PFKFB, cardiac
- Modification TypePhosphorylated
- Scientific DescriptionThe protein encoded by this gene is involved in both the synthesis and degradation of fructose-2,6-bisphosphate, a regulatory molecule that controls glycolysis in eukaryotes. The encoded protein has a 6-phosphofructo-2-kinase activity that catalyzes the synthesis of fructose-2,6-bisphosphate, and a fructose-2,6-biphosphatase activity that catalyzes the degradation of fructose-2,6-bisphosphate. This protein regulates fructose-2,6-bisphosphate levels in the heart, while a related enzyme encoded by a different gene regulates fructose-2,6-bisphosphate levels in the liver and muscle. This enzyme functions as a homodimer. Two transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
- Storage Instruction-20°C
- UNSPSC12352203