anti-PFKFB2 phospho (Ser483) antibody

Arigo Biolaboratories

anti-PFKFB2 phospho (Ser483) antibody

23

Western Blot

Research Use Only

Polyclonal

Unconjugated

PFKFB2

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2

6PF-2-K/Fru-2,6-P2ase 2; 6PF-2-K/Fru-2,6-P2ASE heart-type isozyme; 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2; fructose-2,6-bisphosphatase, cardiac isozyme; PFK/FBPase 2; PFK-2/FBPase-2; PFKFB, cardiac

Rabbit

IgG

Phosphorylated

The protein encoded by this gene is involved in both the synthesis and degradation of fructose-2,6-bisphosphate, a regulatory molecule that controls glycolysis in eukaryotes. The encoded protein has a 6-phosphofructo-2-kinase activity that catalyzes the synthesis of fructose-2,6-bisphosphate, and a fructose-2,6-biphosphatase activity that catalyzes the degradation of fructose-2,6-bisphosphate. This protein regulates fructose-2,6-bisphosphate levels in the heart, while a related enzyme encoded by a different gene regulates fructose-2,6-bisphosphate levels in the liver and muscle. This enzyme functions as a homodimer. Two transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Human

-20°C

12352203