Immunohistochemistry analysis in human cerebral cortex and tonsil tissues using AMAb91428 antibody. Corresponding SORT1 RNA-seq data are presented for the same tissues.
Immunohistochemistry analysis in human cerebral cortex and tonsil tissues using AMAb91428 antibody. Corresponding SORT1 RNA-seq data are presented for the same tissues.
Anti-SORT1 Antibody
AMAB91428
ApplicationsWestern Blot, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman, Mouse
TargetSORT1
Overview
- SupplierAtlas Antibodies
- Product NameAnti-SORT1
- Delivery Days Customer4
- ApplicationsWestern Blot, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDCL6528
- ConjugateUnconjugated
- Gene ID6272
- Target nameSORT1
- Target descriptionsortilin 1
- Target synonymsGp95, LDLCQ6, NT3, NTR3, sortilin, 100 kDa NT receptor, glycoprotein 95, neurotensin receptor 3
- HostMouse
- IsotypeIgG1
- Protein IDQ99523
- Protein NameSortilin
- Scientific DescriptionRecombinant Protein Epitope Signature Tag (PrEST) antigen sequence
- ReactivityHuman, Mouse
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC41116161
Datasheet
MSDS
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![Binding of Progranulin (human) (rec.) (untagged) (Prod. No. AG-40A-0188Y) to Sortilin (human) (rec.) (His) (Prod. No. AG-40B-0229) is inhibited by the antibody Sortilin (human), mAb (rec.) (blocking) [Latozinemab Bioimilar] (Prod. No. AG-27B-7000PF). Methods: Progranulin (human) (rec.) (untagged) is coated on an ELISA plate at 1 microg/ml. Sortilin (human), mAb (rec.) (blocking) [Latozinemab Biosimilar] or an unrelated mAb (Control) is added (starting at 20 microg/ml with a twofold serial dilution) together with 250 ng/ml of Sortilin (rec.) (His) for 1 hour. The binding is detected using an anti-His (HRP) incubated for 30 minutes followed by addition of the substrate TMB. The decreasing ODs observed in the Y axis represent the binding between Progranulin and Sortilin that is inhibited in a dose-dependent manner by Sortilin (human), mAb (rec.) (blocking) [Latozinemab Biosimilar]. This inhibition is not observed with the control antibody.](https://adipogen.com/pub/media/catalog/product/a/g/ag-27b-7000pf-binding_blocking_assay-500px.jpg)
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