Anti-Spike protein [D70678-5521-S2]

Absolute Antibody

Anti-Spike protein [D70678-5521-S2]

9

This antibody is specific for the spike protein of SARS CoV2. SARS-CoV-2 is a positive-sense single-stranded RNA virus[5] that is contagious in humans.

To characterize this antibody, an indirect ELISA was performed using the human version of this antibody. The antigen used was the SARS CoV2 spike protein. The human version of this antibody is capable of binding the S1 protein but incapable of blocking S1:ACE2 interaction. This antibody is reported to bind non-competitively with another anti-SARS CoV2 antibody 18F4. Further both biolayer interferometry and surface plasmon resonance were used to determine the kinetics of the human version of this antibody. Both experiments used the SARS CoV2 spike protein as the antigen (Mullen et al, 2021).

Functional Assay, ELISA, Other Application

Research Use Only

Monoclonal

D70678-5521-S2

S

surface glycoprotein

GU280_gp02; spike glycoprotein; surface glycoprotein

Mouse

Spike glycoprotein

This chimeric mouse antibody was made using the variable domain sequences of the original Human IgG1 format, for improved compatibility with existing reagents, assays and techniques.

Virus

-20°C,2°C to 8°C

12352203