Anti-TLR7 [LTM3]

Absolute Antibody

Anti-TLR7 [LTM3]

9

This antibody binds human toll-like receptor 7 (TLR7). It also cross reacts with monkey TLR7. It is an endosomal receptor that plays a key role in innate and adaptive immunity. It also controls host immune response against pathogens through recognition of

This antibody was used in combination with another anti-TLR7 antibody called rE3 to detect human TLR7 in a sandwich ELISA. LTM3 was used as used as a capturing antibody and biotinylated rE3 antibody (rE3-bio) was used a detecting antibody. This antibody can be used for the detection of human TLR7 in serum or plasma derived from human peripheral blood. The binding ability of this antibody for Ba/F3 cell line expressing human TLR7, mouse TLR7 and monkey TLR7 was checked using flow cytometry. This antibody can successfully detect human and monkey TLR7, but not mouse TLR7 in a flow cytometry (US20210199667).

Flow Cytometry, ELISA

Research Use Only

Monoclonal

LTM3

TLR7

toll like receptor 7

IMD74; TLR7-like; toll-like receptor 7; toll-like receptor 7-like

Rabbit

IgG

Toll-like receptor 7

This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format for improved compatibility with existing reagents assays and techniques.

Human, Monkey

-20°C,2°C to 8°C

12352203