Anti-TLR7 [rE3]

Ab03264-23.0
ApplicationsFlow Cytometry, ImmunoPrecipitation, ELISA
Product group Antibodies
ReactivityHuman, Monkey
TargetTLR7
Overview
- SupplierAbsolute Antibody
- Product NameAnti-TLR7 [rE3]
- Delivery Days Customer7
- Antibody SpecificityThis antibody binds human toll-like receptor 7 (TLR7). It also cross reacts with monkey TLR7. It is an endosomal receptor that plays a key role in innate and adaptive immunity. It also controls host immune response against pathogens through recognition of
- Application Supplier NoteThis antibody was used in combination with another anti-TLR7 antibody called TLM3 to detect human TLR7 in a sandwich ELISA. LTM3 was used as used as a capturing antibody and biotinylated rE3 antibody (rE3-bio) was used a detecting antibody. This antibody can be used for the detection of human TLR7 in serum or plasma derived from human peripheral blood. The binding ability of this antibody for Ba/F3 cell line expressing human TLR7, mouse TLR7 and monkey TLR7 was checked using flow cytometry. This antibody can successfully detect human and monkey TLR7, but not mouse TLR7 in a flow cytometry. This antibody was also used in the detection of soluble human TLR7 in a sample using immunoprecipitation (US20210199667).
- ApplicationsFlow Cytometry, ImmunoPrecipitation, ELISA
- Applications SupplierELISA; FC; IP
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDrE3
- Gene ID51284
- Target nameTLR7
- Target descriptiontoll like receptor 7
- Target synonymsIMD74; TLR7-like; toll-like receptor 7; toll-like receptor 7-like
- HostRabbit
- IsotypeIgG
- Protein IDQ9NYK1
- Protein NameToll-like receptor 7
- Scientific DescriptionThis chimeric rabbit antibody was made using the variable domain sequences of the original Rat IgG2a format for improved compatibility with existing reagents assays and techniques.
- ReactivityHuman, Monkey
- Reactivity SupplierHuman, monkey
- Reactivity Supplier NoteThe original antibody was generated by immunizing wild-type Wister rat with Ba/F3 cell line expressing hTLR7-Flag-Hisx6/hUnc93B1-HAx2 mixed with a suitable adjuvant.
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352203