Bio-Connect

Anti-TLR7 [rE3]

Research Use Only
Ab03264-23.0
Absolute Antibody
ApplicationsFlow Cytometry, ImmunoPrecipitation, ELISA
Product group Antibodies
ReactivityHuman, Monkey
TargetTLR7
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Overview

  • Supplier
    Absolute Antibody
  • Product Name
    Anti-TLR7 [rE3]
  • Delivery Days Customer
    7
  • Antibody Specificity
    This antibody binds human toll-like receptor 7 (TLR7). It also cross reacts with monkey TLR7. It is an endosomal receptor that plays a key role in innate and adaptive immunity. It also controls host immune response against pathogens through recognition of
  • Application Supplier Note
    This antibody was used in combination with another anti-TLR7 antibody called TLM3 to detect human TLR7 in a sandwich ELISA. LTM3 was used as used as a capturing antibody and biotinylated rE3 antibody (rE3-bio) was used a detecting antibody. This antibody can be used for the detection of human TLR7 in serum or plasma derived from human peripheral blood. The binding ability of this antibody for Ba/F3 cell line expressing human TLR7, mouse TLR7 and monkey TLR7 was checked using flow cytometry. This antibody can successfully detect human and monkey TLR7, but not mouse TLR7 in a flow cytometry. This antibody was also used in the detection of soluble human TLR7 in a sample using immunoprecipitation (US20210199667).
  • Applications
    Flow Cytometry, ImmunoPrecipitation, ELISA
  • Applications Supplier
    ELISA; FC; IP
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    rE3
  • Gene ID51284
  • Target name
    TLR7
  • Target description
    toll like receptor 7
  • Target synonyms
    IMD74; TLR7-like; toll-like receptor 7; toll-like receptor 7-like
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ9NYK1
  • Protein Name
    Toll-like receptor 7
  • Scientific Description
    This chimeric rabbit antibody was made using the variable domain sequences of the original Rat IgG2a format for improved compatibility with existing reagents assays and techniques.
  • Reactivity
    Human, Monkey
  • Reactivity Supplier
    Human, monkey
  • Reactivity Supplier Note
    The original antibody was generated by immunizing wild-type Wister rat with Ba/F3 cell line expressing hTLR7-Flag-Hisx6/hUnc93B1-HAx2 mixed with a suitable adjuvant.
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352203