Anti-VEGFR-3 [ABDD073]

Absolute Antibody

Anti-VEGFR-3 [ABDD073]

9

The antibody is specific for VEGFR-3.

The antibody showed neutralizing activity by ELISA analysis. The antibody detected VEGFR-3 from HEL cell lysates by western blot analysis. The antibody could recognize VEGRF-3 on fetal heart, fetal kidney and fetal lung tissue by immunohistochemistry. The binding activity of the antibody to VEGFR-3 expressed on the surface of HEL cells was confirmed by FACS flow cytometry. In vitro experiments showed the antibody could block the interaction between VEGFR-3 and VEGF-D. The antibody could inhibit HEL cell proliferation. The antibody could inhibit the generation of chicken embryo allantoic membrane blood vessels induced by recombinant GST-VEGF-D (CN1800373A).

Flow Cytometry, ELISA, ImmunoHistoChemistry

Research Use Only

Monoclonal

ABDD073

FLT4

fms related receptor tyrosine kinase 4

CHTD7; Feline McDonough Sarcoma (FMS)-like tyrosine kinase 4; FLT-4; FLT41; fms related tyrosine kinase 4; fms-like tyrosine kinase 4; LMPH1A; LMPHM1; PCL; primary congenital lymphedema; tyrosine-protein kinase receptor FLT4; vascular endothelial growth factor receptor 3; VEGF receptor-3; VEGFR3; VEGFR-3

Mouse

IgG2b

Vascular endothelial growth factor receptor 3

Human

-20°C,2°C to 8°C

12352203