Anti-VISTA [11A4]

Absolute Antibody

Anti-VISTA [11A4]

7

The antibody is specific for VISTA protein. VISTA is an immunoregulatory receptor which inhibits the T-cell response, which may promote differentiation of embryonic stem cells, by inhibiting BMP4 signaling.

The antibody 11A4 and the commercial antibody D5L5T were used to stain epithelial vascular sarcoma, placental trophoblasts and urethral carcinoma in immunohistochemistry. Results showed the antibody specificity is equivalent to the commercial antibody. Further, the staining intensity of the antibody 11A4 was higher than the commercial antibody (CN112940125A).

Western Blot, ELISA, ImmunoHistoChemistry

IHC; WB; ELISA

Research Use Only

Monoclonal

11A4

VSIR

V-set immunoregulatory receptor

B7H5; B7-H5; C10orf54; DD1alpha; Death Domain1alpha; Dies1; GI24; PD-1H; PDCD1 homolog; platelet receptor GI24; PP2135; SISP1; sisp-1; stress-induced secreted protein-1; V-domain Ig suppressor of T cell activation; VISTA; V-set domain-containing immunoregulatory receptor; V-type immunoglobulin domain-containing suppressor of T-cell activation

Rabbit

IgG

V-type immunoglobulin domain-containing suppressor of T-cell activation

This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG2a format for improved compatibility with existing reagents assays and techniques.

Human

Human

The original antibody was generated by immunizing a mouse with the recombinant VISTA protein.

-20°C,2°C to 8°C

12352203