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Western Blot analysis of whole cell lysate from K562 cells probed with Rabbit anti APAF1 (GTX22001) either in the absence (A) or presence (B) of blocking peptide
Western Blot analysis of whole cell lysate from K562 cells probed with Rabbit anti APAF1 (GTX22001) either in the absence (A) or presence (B) of blocking peptide
Western Blot analysis of whole cell lysate from K562 cells probed with Rabbit anti APAF1 (GTX22001) either in the absence (A) or presence (B) of blocking peptide

APAF1 antibody

GTX22001
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
DownloadDatasheet
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetAPAF1
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Overview

  • Supplier
    GeneTex
  • Product Name
    APAF1 antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1-2microg/ml. IHC: 1-2microg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    Unconjugated
  • Gene ID317
  • Target name
    APAF1
  • Target description
    apoptotic peptidase activating factor 1
  • Target synonyms
    APAF-1; apoptotic protease-activating factor 1; CED4
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDO14727
  • Protein Name
    Apoptotic protease-activating factor 1
  • Scientific Description
    This gene encodes a cytoplasmic protein that initiates apoptosis. This protein contains several copies of the WD-40 domain, a caspase recruitment domain (CARD), and an ATPase domain (NB-ARC). Upon binding cytochrome c and dATP, this protein forms an oligomeric apoptosome. The apoptosome binds and cleaves caspase 9 preproprotein, releasing its mature, activated form. Activated caspase 9 stimulates the subsequent caspase cascade that commits the cell to apoptosis. Alternative splicing results in several transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
  • Reactivity
    Human, Mouse, Rat
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Promoting roles of KLF5 in myocardial infarction in mice involving microRNA-27a suppression and the following GFPT2/TGF-beta/Smad2/3 axis activation. Tian Z et al., 2021 May, Cell Cycle
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