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APAF1 antibody

GTX22445
GeneTex
ApplicationsWestern Blot
DownloadDatasheet
Product group Antibodies
ReactivityHuman
TargetAPAF1
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Overview

  • Supplier
    GeneTex
  • Product Name
    APAF1 antibody
  • Delivery Days Customer
    9
  • Applications
    Western Blot
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.2 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID317
  • Target name
    APAF1
  • Target description
    apoptotic peptidase activating factor 1
  • Target synonyms
    APAF-1; apoptotic protease-activating factor 1; CED4
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDO14727
  • Protein Name
    Apoptotic protease-activating factor 1
  • Scientific Description
    This gene encodes a cytoplasmic protein that initiates apoptosis. This protein contains several copies of the WD-40 domain, a caspase recruitment domain (CARD), and an ATPase domain (NB-ARC). Upon binding cytochrome c and dATP, this protein forms an oligomeric apoptosome. The apoptosome binds and cleaves caspase 9 preproprotein, releasing its mature, activated form. Activated caspase 9 stimulates the subsequent caspase cascade that commits the cell to apoptosis. Alternative splicing results in several transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
  • Reactivity
    Human
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203