APC / Adenomatous Polyposis Coli / FAP (Tumor Suppressor)(ALi 12-28), 0.2mg/mL [26628-22-8]

Biotium

APC / Adenomatous Polyposis Coli / FAP (Tumor Suppressor)(ALi 12-28), 0.2mg/mL [26628-22-8]

9

ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen

26628-22-8

Research Use Only

Monoclonal

ALi 12-28

0.2 mg/ml

APC

APC regulator of Wnt signaling pathway

BTPS2, DESMD, DP2, DP2.5, DP3, GS, PPP1R46, adenomatous polyposis coli protein, APC, WNT signaling pathway regulator, WNT signaling pathway regulator, adenomatosis polyposis coli tumor suppressor, adenomatous polyposis coli (APC), deleted in polyposis 2.5, epididymis secretory sperm binding protein, protein phosphatase 1, regulatory subunit 46

Mouse

IgG1

Adenomatous polyposis coli protein

Adenomatous Polyposis Coli (APC) is a protein with many cellular functions. It is a tumor suppressor and negative regulator of Wnt signaling. APC has roles in cell adhesion and cell migration. Mutations in APC are assuciated with several diseases. The adenomatous polyposis syndromes, familial adenomatous polyposis (FAP) and Gardners syndrome (GS), are characterized by numerous adenomatous polyps throughout the entire colon. These polyps invariably progress to colon cancer in addition to other extracolonic manifestations. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Animal

Human

2°C to 8°C,RT

41116161