
Sandwich ELISA detection of non-transfected and transfected 293T whole cell extracts using GTX113131 as capture antibody at concentration of 5 μg/mL and GTX634218 as detection antibody at concentration of 1 μg/mL. Mouse IgG antibody (HRP) (GTX213111-01) was diluted at 1:10000 and used to detect the primary antibody.
Arginase 1 antibody
GTX113131
ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetARG1
Overview
- SupplierGeneTex
- Product NameArginase 1 antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:5000-1:20000. IHC-P: 1:100-1:1000. ELISA: 1:1000-1:10000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.41 mg/ml
- ConjugateUnconjugated
- Gene ID383
- Target nameARG1
- Target descriptionarginase 1
- Target synonymsarginase-1, arginase, liver, liver-type arginase, type I arginase
- HostRabbit
- IsotypeIgG
- Protein IDP05089
- Protein NameArginase-1
- Scientific DescriptionArginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exist (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. The type I isoform encoded by this gene, is a cytosolic enzyme and expressed predominantly in the liver as a component of the urea cycle. Inherited deficiency of this enzyme results in argininemia, an autosomal recessive disorder characterized by hyperammonemia. [provided by RefSeq]
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Hiengrach P, Chindamporn A, Leelahavanichkul A. Kazachstania pintolopesii in Blood and Intestinal Wall of Macrophage-Depleted Mice with Cecal Ligation and Puncture, the Control of Fungi by Macrophages during Sepsis. J Fungi (Basel). 2023,9(12). doi: 10.3390/jof9121164Read this paper
- Ottaiano A, Scala S, Normanno N, et al. Cetuximab, irinotecan and fluorouracile in fiRst-line treatment of immunologically-selected advanced colorectal cancer patients: the CIFRA study protocol. BMC Cancer. 2019,19(1):899. doi: 10.1186/s12885-019-6109-zRead this paper
- Polis B, Srikanth KD, Gurevich V, et al. L-Norvaline, a new therapeutic agent against Alzheimer's disease. Neural Regen Res. 2019,14(9):1562-1572. doi: 10.4103/1673-5374.255980Read this paper
- Polis B, Srikanth KD, Elliott E, et al. L-Norvaline Reverses Cognitive Decline and Synaptic Loss in a Murine Model of Alzheimer's Disease. Neurotherapeutics. 2018,15(4):1036-1054. doi: 10.1007/s13311-018-0669-5Read this paper
- Simkin J, Gawriluk TR, Gensel JC, et al. Macrophages are necessary for epimorphic regeneration in African spiny mice. Elife. 2017,6:pii: e24623. doi: 10.7554/eLife.24623.Read this paper
- Maina V, Sutti S, Locatelli I, et al. Bias in macrophage activation pattern influences non-alcoholic steatohepatitis (NASH) in mice. Clin Sci (Lond). 2012,122(11):545-53. doi: 10.1042/CS20110366Read this paper











![IHC-P analysis of human liver tissue using GTX04426 Arginase 1 antibody [MSVA-511R] HistoMAX?. Strong nuclear and cytoplasmic arginase 1 expression in all hepatocytes in a normal liver.](https://www.genetex.com/upload/website/prouct_img/normal/GTX04426/GTX04426_20230728_IHC-P_4_23072722_512.webp)


![Non-transfected (–) and transfected (+) 293T whole cell extracts (30 μg) were separated by 12% SDS-PAGE, and the membrane was blotted with Arginase 1 antibody [HL1891] (GTX637640) diluted at 1:2500. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.](https://www.genetex.com/upload/website/prouct_img/normal/GTX637640/GTX637640_T-44837_20230203_WB_multiple_B_23020621_412.webp)