Immunofluorescence staining of Hela cells with CSB-PA01445A0Rb at 1:250, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
ARHGEF7 Antibody
CSB-PA01445A0RB
ApplicationsImmunoFluorescence, ImmunoPrecipitation, ELISA
Product group Antibodies
ReactivityHuman
TargetARHGEF7
Overview
- SupplierCusabio
- Product NameARHGEF7 Antibody
- Delivery Days Customer20
- ApplicationsImmunoFluorescence, ImmunoPrecipitation, ELISA
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID8874
- Target nameARHGEF7
- Target descriptionRho guanine nucleotide exchange factor 7
- Target synonymsBETA-PIX; COOL1; COOL-1; Nbla10314; P50; P50BP; P85; P85COOL1; P85SPR; PAK3; PAK-interacting exchange factor beta; PIXB; Rho guanine nucleotide exchange factor (GEF) 7; rho guanine nucleotide exchange factor 7; SH3 domain-containing proline-rich protein
- HostRabbit
- IsotypeIgG
- Protein IDQ14155
- Protein NameRho guanine nucleotide exchange factor 7
- Scientific DescriptionActs as a RAC1 guanine nucleotide exchange factor (GEF) and can induce membrane ruffling. Functions in cell migration, attachment and cell spreading. Promotes targeting of RAC1 to focal adhesions By similarity. May function as a positive regulator of apoptosis. Downstream of NMDA receptors and CaMKK-CaMK1 signaling cascade, promotes the formation of spines and synapses in hippocampal neurons.
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC12352203