ARTS antibody [ARTS51]

GeneTex

ARTS antibody [ARTS51]

9

This monoclonal anti-ARTS antibody was used to detect ARTS (Sept4_i2) protein in whole lysates of HeLa cells. HeLa ARTS knockdown (ARTS KD) stable cell line was established by using short hairpin RNAs (shRNAs) which abrogated specifically the endogenous l

WB: 0.5-1 microg/ml. IP: 10microl. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ELISA, ImmunoCytoChemistry

Research Use Only

Monoclonal

ARTS51

2 mg/ml

Unconjugated

SEPTIN4

septin 4

apoptosis-related protein in the TGF-beta signaling pathway; ARTS; BRADEION; bradeion beta; brain protein H5; C17orf47; CE5B3; CE5B3 beta; cell division control-related protein 2; cerebral protein 7; H5; hCDCREL-2; hucep-7; MART; peanut-like protein 2; PNUTL2; SEP4; SEPT4; septin-4; septin-M; uncharacterized protein C17orf47

Mouse

IgG2b

Septin-4

Apoptosis is related to many diseases and development. Mitochondrial proteins, such as cytochrome c, Apaf1, and AIF play important role in apoptosis. A novel mitochondrial septin-like protein was identified recently and designated ARTS for apoptosis related protein in TGF beta signaling pathway. ARTS that is encoded by the human septin H5/PNUTL2/CDCrel2b gene is located to mitochondria and translocates to the nucleus when apoptosis occurs. ARTS is expressed in many tissues. It enhances cell death induced by TGF beta and, to a lesser extent, by other apoptotic agents, such as TNF alpha and Fas ligand.

Human

-20°C or -80°C,2°C to 8°C

12352203