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ATF2 (phospho Ser112) antibody

Research Use Only
GTX79131
GeneTex
ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetATF2
Price on request
Packing Size
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Overview

  • Supplier
    GeneTex
  • Product Name
    ATF2 (phospho Ser112) antibody
  • Delivery Days Customer
    9
  • Antibody Specificity
    This antibody is raised against human ATF2 phosphorylated at Ser112. Based on sequence homology, it is predicted to react with mouse/rat ATF2 when phosphorylated at the corresponding residues - ATF2 Ser94.
  • Applications
    ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    Unconjugated
  • Gene ID1386
  • Target name
    ATF2
  • Target description
    activating transcription factor 2
  • Target synonyms
    activating transcription factor 2 splice variant ATF2-var2; cAMP response element-binding protein CRE-BP1; cAMP responsive element binding protein 2, formerly; cAMP-dependent transcription factor ATF-2; CREB2; CREB-2; CRE-BP1; cyclic AMP-dependent transcription factor ATF-2; cyclic AMP-responsive element-binding protein 2; HB16; histone acetyltransferase ATF2; TREB7
  • Host
    Rabbit
  • Isotype
    IgG
  • Modification Type
    Phosphorylated
  • Scientific Description
    This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions This protein binds to the cAMP-responsive element (CRE), an octameric palindrome. It forms a homodimer or a heterodimer with c-Jun and stimulates CRE-dependent transcription. This protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro; thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components. The encoded protein may also be involved in cells DNA damage response independent of its role in transcriptional regulation. Several alternatively spliced transcript variants have been found for this gene [provided by RefSeq, Jan 2014]
  • Reactivity
    Human
  • Storage Instruction
    2°C to 8°C,-20°C or -80°C
  • UNSPSC
    12352203