ATF2 (phospho Thr71) antibody [GT1275]

GeneTex

ATF2 (phospho Thr71) antibody [GT1275]

9

WB: 1:500 - 1:2000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot

Research Use Only

Monoclonal

GT1275

0.52 mg/ml

Unconjugated

ATF2

activating transcription factor 2

CRE-BP1, CREB-2, CREB2, HB16, TREB7, cyclic AMP-dependent transcription factor ATF-2, cAMP response element-binding protein CRE-BP1, cAMP responsive element binding protein 2, formerly, cAMP-dependent transcription factor ATF-2, cyclic AMP-responsive element-binding protein 2, histone acetyltransferase ATF2

Rabbit

IgG

Cyclic AMP-dependent transcription factor ATF-2

This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions This protein binds to the cAMP-responsive element (CRE), an octameric palindrome. It forms a homodimer or a heterodimer with c-Jun and stimulates CRE-dependent transcription. This protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro; thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components. The encoded protein may also be involved in cells DNA damage response independent of its role in transcriptional regulation. Several alternatively spliced transcript variants have been found for this gene [provided by RefSeq, Jan 2014]

Human, Mouse, Rat

-20°C or -80°C,2°C to 8°C

12352203