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WB analysis of HeLa whole cell lysate using GTX81096 ATF6 antibody, Internal. Loading : 20 microg per lane Dilution : 1:16000
WB analysis of HeLa whole cell lysate using GTX81096 ATF6 antibody, Internal. Loading : 20 microg per lane Dilution : 1:16000
WB analysis of HeLa whole cell lysate using GTX81096 ATF6 antibody, Internal. Loading : 20 microg per lane Dilution : 1:16000

ATF6 antibody, Internal

GTX81096
GeneTex
TargetATF6
Product group Antibodies
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Overview

  • Supplier
    GeneTex
  • Product Name
    ATF6 antibody, Internal
  • Delivery Days Customer
    9
  • Antibody Specificity
    The immunogen sequence of this antibody is within the cleaved form of ATF6 alpha.
  • Application Supplier Note
    WB: 1:1000. IHC-P: 1:10-1:50. FACS: 1:10-1:50. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Formulation
    Liquid
  • Gene ID22926
  • Target name
    ATF6
  • Target description
    activating transcription factor 6
  • Target synonyms
    ACHM7; ATF6A; cAMP-dependent transcription factor ATF-6 alpha; cyclic AMP-dependent transcription factor ATF-6 alpha
  • Protein IDP18850
  • Protein Name
    Cyclic AMP-dependent transcription factor ATF-6 alpha
  • Scientific Description
    This gene encodes a transcription factor that activates target genes for the unfolded protein response (UPR) during endoplasmic reticulum (ER) stress. Although it is a transcription factor, this protein is unusual in that it is synthesized as a transmembrane protein that is embedded in the ER. It functions as an ER stress sensor/transducer, and following ER stress-induced proteolysis, it functions as a nuclear transcription factor via a cis-acting ER stress response element (ERSE) that is present in the promoters of genes encoding ER chaperones. This protein has been identified as a survival factor for quiescent but not proliferative squamous carcinoma cells. There have been conflicting reports about the association of polymorphisms in this gene with diabetes in different populations, but another polymorphism has been associated with increased plasma cholesterol levels. This gene is also thought to be a potential therapeutic target for cystic fibrosis. [provided by RefSeq, Aug 2011]
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203