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ProductsBack/ATP citrate lyase antibody [N1N2], N-term

ATP citrate lyase antibody [N1N2], N-term

GTX112387
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetACLY
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Overview

  • Supplier
    GeneTex
  • Product Name
    ATP citrate lyase antibody [N1N2], N-term
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:1000-1:10000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.93 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID47
  • Target name
    ACLY
  • Target description
    ATP citrate lyase
  • Target synonyms
    ACL, ATPCL, CLATP, ATP-citrate synthase, ATP-citrate (pro-S-)-lyase, citrate cleavage enzyme
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP53396
  • Protein Name
    ATP-citrate synthase
  • Scientific Description
    ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis. In nervous tissue, ATP citrate-lyase may be involved in the biosynthesis of acetylcholine. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq]
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • García-Arroyo FE, Monroy-Sánchez F, Muñoz-Jiménez I, et al. Allopurinol Prevents the Lipogenic Response Induced by an Acute Oral Fructose Challenge in Short-Term Fructose Fed Rats. Biomolecules. 2019,9(10). doi: 10.3390/biom9100601
    Read this paper
  • Li X, Yu W, Qian X, et al. Nucleus-Translocated ACSS2 Promotes Gene Transcription for Lysosomal Biogenesis and Autophagy. Mol Cell. 2017,66(5):684-697.e9. doi: 10.1016/j.molcel.2017.04.026
    Read this paper

Datasheet

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