Western blot analysis of extracts of various cell lines using ATP6V1B2 Polyclonal Antibody at 1:1000 dilution.
Western blot analysis of extracts of various cell lines using ATP6V1B2 Polyclonal Antibody at 1:1000 dilution.
ATP6V1B2 Polyclonal Antibody
E-AB-62636
Product group Antibodies
Overview
- SupplierElabscience
- Product NameATP6V1B2 Polyclonal Antibody
- Delivery Days Customer12
- CertificationResearch Use Only
- Scientific DescriptionThis gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A, three B, and two G subunits, as well as a C, D, E, F, and H subunit. The V1 domain contains the ATP catalytic site. The protein encoded by this gene is one of two V1 domain B subunit isoforms and is the only B isoform highly expressed in osteoclasts.
- UNSPSC12352203