ATR antibody
GTX10312
ApplicationsWestern Blot
Product group Antibodies
ReactivityHuman, Mouse
TargetATR
Overview
- SupplierGeneTex
- Product NameATR antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 0.033 - 0.067 microg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID545
- Target nameATR
- Target descriptionATR checkpoint kinase
- Target synonymsFCTCS, FRP1, MEC1, SCKL, SCKL1, serine/threonine-protein kinase ATR, ATR serine/threonine kinase, FRAP-related protein-1, MEC1, mitosis entry checkpoint 1, homolog, ataxia telangiectasia and Rad3-related protein
- HostRabbit
- IsotypeIgG
- Protein IDQ13535
- Protein NameSerine/threonine-protein kinase ATR
- Scientific DescriptionThe protein encoded by this gene is a serine/threonine kinase and DNA damage sensor, activating cell cycle checkpoint signaling upon DNA stress. The encoded protein can phosphorylate and activate several proteins involved in the inhibition of DNA replication and mitosis, and can promote DNA repair, recombination, and apoptosis. This protein is also important for fragile site stability and centrosome duplication. Defects in this gene are a cause of Seckel syndrome 1. [provided by RefSeq, Aug 2017]
- ReactivityHuman, Mouse
- Storage Instruction2°C to 8°C
- UNSPSC12352203


![Untreated (–) and treated (+) mouse tissue extract (50 μg) were separated by 5% SDS-PAGE, and the membrane was blotted with ATR (phospho Ser428) antibody [HL3246] (GTX640889) diluted at 1:2500. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.](https://www.genetex.com/upload/website/prouct_img/normal/GTX640889/GTX640889_T-45516_20241004_WB_M_treatment_CIP_24100900_134.webp)


