ATR antibody

GTX10312
Overview
- SupplierGeneTex
- Product NameATR antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 0.033 - 0.067 microg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- FormulationLiquid
- Gene ID545
- Target nameATR
- Target descriptionATR serine/threonine kinase
- Target synonymsataxia telangiectasia and Rad3-related protein; FCTCS; FRAP-related protein-1; FRP1; MEC1; MEC1, mitosis entry checkpoint 1, homolog; SCKL; SCKL1; serine/threonine-protein kinase ATR
- HostRabbit
- IsotypeIgG
- Protein IDQ13535
- Protein NameSerine/threonine-protein kinase ATR
- Scientific DescriptionThe protein encoded by this gene is a serine/threonine kinase and DNA damage sensor, activating cell cycle checkpoint signaling upon DNA stress. The encoded protein can phosphorylate and activate several proteins involved in the inhibition of DNA replication and mitosis, and can promote DNA repair, recombination, and apoptosis. This protein is also important for fragile site stability and centrosome duplication. Defects in this gene are a cause of Seckel syndrome 1. [provided by RefSeq, Aug 2017]
- ReactivityHuman, Mouse
- Storage Instruction2°C to 8°C
- UNSPSC12352203