ATR (phospho Thr1989) antibody [HL1836]

GeneTex

ATR (phospho Thr1989) antibody [HL1836]

9

WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

ImmunoFluorescence, Western Blot, ImmunoCytoChemistry

Research Use Only

Monoclonal

HL1836

1 mg/ml

Unconjugated

ATR

ATR serine/threonine kinase

ataxia telangiectasia and Rad3-related protein; FCTCS; FRAP-related protein-1; FRP1; MEC1; MEC1, mitosis entry checkpoint 1, homolog; SCKL; SCKL1; serine/threonine-protein kinase ATR

Rabbit

IgG

Serine/threonine-protein kinase ATR

The protein encoded by this gene is a serine/threonine kinase and DNA damage sensor, activating cell cycle checkpoint signaling upon DNA stress. The encoded protein can phosphorylate and activate several proteins involved in the inhibition of DNA replication and mitosis, and can promote DNA repair, recombination, and apoptosis. This protein is also important for fragile site stability and centrosome duplication. Defects in this gene are a cause of Seckel syndrome 1. [provided by RefSeq, Aug 2017]

Human

-20°C or -80°C,2°C to 8°C

12352203