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ProductsBack/ATRX antibody [HL1210]
ATRX antibody [HL1210] detects ATRX protein at nucleus by immunofluorescent analysis. Sample: HeLa cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: ATRX stained by ATRX antibody [HL1210] (GTX635478) diluted at 1:100. Red: phalloidin, a cytoskeleton marker, diluted at 1:200. Scale bar= 10 μm.
ATRX antibody [HL1210] detects ATRX protein at nucleus by immunofluorescent analysis. Sample: HeLa cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: ATRX stained by ATRX antibody [HL1210] (GTX635478) diluted at 1:100. Red: phalloidin, a cytoskeleton marker, diluted at 1:200. Scale bar= 10 μm.
ATRX antibody [HL1210] detects ATRX protein at nucleus by immunofluorescent analysis. Sample: HeLa cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: ATRX stained by ATRX antibody [HL1210] (GTX635478) diluted at 1:100. Red: phalloidin, a cytoskeleton marker, diluted at 1:200. Scale bar= 10 μm.

ATRX antibody [HL1210]

GTX635478
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry
Product group Antibodies
ReactivityHuman
TargetATRX
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Overview

  • Supplier
    GeneTex
  • Product Name
    ATRX antibody [HL1210]
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    HL1210
  • Concentration
    1.88 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID546
  • Target name
    ATRX
  • Target description
    ATRX chromatin remodeler
  • Target synonyms
    JMS, MRX52, RAD54, RAD54L, XH2, XNP, ZNF-HX, transcriptional regulator ATRX, ATP-dependent helicase ATRX, X-linked helicase II, X-linked nuclear protein
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP46100
  • Protein Name
    Transcriptional regulator ATRX
  • Scientific Description
    The protein encoded by this gene contains an ATPase/helicase domain, and thus it belongs to the SWI/SNF family of chromatin remodeling proteins. This protein is found to undergo cell cycle-dependent phosphorylation, which regulates its nuclear matrix and chromatin association, and suggests its involvement in the gene regulation at interphase and chromosomal segregation in mitosis. Mutations in this gene are associated with X-linked syndromes exhibiting cognitive disabilities as well as alpha-thalassemia (ATRX) syndrome. These mutations have been shown to cause diverse changes in the pattern of DNA methylation, which may provide a link between chromatin remodeling, DNA methylation, and gene expression in developmental processes. Multiple alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2017]
  • Reactivity
    Human
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    41116161

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