ATXN1 Polyclonal Antibody

Elabscience

ATXN1 Polyclonal Antibody

12

Western Blot, ImmunoHistoChemistry

ELISA WB IHC

Research Use Only

Polyclonal

0.3 mg/ml

Unconjugated

ATXN1

ataxin 1

ATX1, D6S504E, SCA1, ataxin-1, alternative ataxin1, spinocerebellar ataxia type 1 protein

Rabbit

IgG

Ataxin-1

The autosomal dominant cerebellar ataxias (ADCA) are a heterogeneous group of neurodegenerative disorders characterized by progressive degeneration of the cerebellum, brain stem and spinal cord. Clinically, ADCA has been divided into three groups: ADCA types I-III. ADCAI is genetically heterogeneous, with five genetic loci, designated spinocerebellar ataxia (SCA) 1, 2, 3, 4 and 6, being assigned to five different chromosomes. ADCAII, which always presents with retinal degeneration (SCA7), and ADCAIII often referred to as the pure cerebellar syndrome (SCA5), are most likely homogeneous disorders. Several SCA genes have been cloned and shown to contain CAG repeats in their coding regions.

-20°C

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