Bio-Connect

AZD3759 (Zorifertinib)

M5164
AbMole BioScience
CAS Number1626387-80-1
Product group Chemicals
Estimated Purity0.9863
Molecular Weight459.9
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Overview

  • Supplier
    AbMole BioScience
  • Product Name
    AZD3759 (Zorifertinib)
  • Delivery Days Customer
    9
  • CAS Number
    1626387-80-1
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Estimated Purity
    0.9863
  • Molecular Formula
    C22H23ClFN5O3
  • Molecular Weight
    459.9
  • Scientific Description
    AZD3759 (Zorifertinib) is a potent, oral active, CNS-penetrant EGFR inhibitor with IC50 of 0.3 nM, 0.2 nM, and 0.2 nM for EGFR (WT), EGFR (L858R), and EGFR (exon 19Del), respectively.
  • SMILES
    COC1=C(OC(=O)N2CCN(C)CC2C)C=C3C(=NC=NC3=C1)NC4=CC=CC(=C4F)Cl
  • UNSPSC
    12352200