Zorifertinib [1626387-80-1]

TargetMol Chemicals

Zorifertinib [1626387-80-1]

4

1626387-80-1

Chemical

Research Use Only

Zorifertinib

99.36%

C22H23ClFN5O3

459.9

Zorifertinib (AZD3759) is an orally active, effective and central nervous system-penetrant EGFR inhibitor. The IC50 values were 0.2, 0.3 and 0.2 nM for EGFR L858R mutant, TK wild-type, and Exon 19Del enzymes, respectively.

3 years

N(C=1C2=C(C=C(OC)C(OC(=O)N3[C@H](C)CN(C)CC3)=C2)N=CN1)C4=C(F)C(Cl)=CC=C4

-20°C

12352200