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BACE1 antibody [N1C2]

GTX103757
GeneTex
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityMouse, Rat
TargetBACE1
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Overview

  • Supplier
    GeneTex
  • Product Name
    BACE1 antibody [N1C2]
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:1000. IHC-P: 1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1.91 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID23621
  • Target name
    BACE1
  • Target description
    beta-secretase 1
  • Target synonyms
    APP beta-secretase; asp 2; ASP2; aspartyl protease 2; BACE; beta-secretase 1; beta-secretase 1 precursor variant 1; beta-site amyloid beta A4 precursor protein-cleaving enzyme; beta-site APP cleaving enzyme 1; beta-site APP-cleaving enzyme; HSPC104; memapsin-2; membrane-associated aspartic protease 2; transmembrane aspartic proteinase Asp2
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP56817
  • Protein Name
    Beta-secretase 1
  • Scientific Description
    This gene encodes a member of the peptidase A1 family of aspartic proteases. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature protease. This transmembrane protease catalyzes the first step in the formation of amyloid beta peptide from amyloid precursor protein. Amyloid beta peptides are the main constituent of amyloid beta plaques, which accumulate in the brains of human Alzheimers disease patients. [provided by RefSeq, Nov 2015]
  • Reactivity
    Mouse, Rat
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Total flavonoid extract from Dracoephalum moldavica L. attenuates beta-amyloid-induced toxicity through anti-amyloidogenesic and neurotrophic pathways. Liu QS et al., 2018 Jan 15, Life Sci
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