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BCL6 antibody [N2C1], Internal

GTX101338
GeneTex
ApplicationsImmunoPrecipitation, Western Blot, ChIP Chromatin ImmunoPrecipitation, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetBCL6
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Overview

  • Supplier
    GeneTex
  • Product Name
    BCL6 antibody [N2C1], Internal
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoPrecipitation, Western Blot, ChIP Chromatin ImmunoPrecipitation, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1.49 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID604
  • Target name
    BCL6
  • Target description
    BCL6 transcription repressor
  • Target synonyms
    BCL5, BCL6A, LAZ3, ZBTB27, ZNF51, B-cell lymphoma 6 protein, B cell CLL/lymphoma 6, B-cell lymphoma 5 protein, B-cell lymphoma 6 protein transcript, BCL-5, BCL-6, cys-his2 zinc finger transcription factor, lymphoma-associated zinc finger gene on chromosome 3, protein LAZ-3, zinc finger and BTB domain-containing protein 27, zinc finger protein 51, zinc finger transcription factor BCL6S
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP41182
  • Protein Name
    B-cell lymphoma 6 protein
  • Scientific Description
    The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal POZ domain. This protein acts as a sequence-specific repressor of transcription, and has been shown to modulate the transcription of START-dependent IL-4 responses of B cells. This protein can interact with a variety of POZ-containing proteins that function as transcription corepressors. This gene is found to be frequently translocated and hypermutated in diffuse large-cell lymphoma (DLCL), and may be involved in the pathogenesis of DLCL. Alternatively spliced transcript variants encoding different protein isoforms have been found for this gene. [provided by RefSeq]
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Changes of allergic inflammation and immunological parameters after Alt a 1 and A. alternata immunotherapy in mice.
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  • BCL6 attenuates renal inflammation via negative regulation of NLRP3 transcription. Chen D et al., 2017 Oct 26, Cell Death Dis
    Read more