BCL6 antibody [N2C1], Internal
GTX101338
ApplicationsImmunoPrecipitation, Western Blot, ChIP Chromatin ImmunoPrecipitation, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetBCL6
Overview
- SupplierGeneTex
- Product NameBCL6 antibody [N2C1], Internal
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoPrecipitation, Western Blot, ChIP Chromatin ImmunoPrecipitation, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1.49 mg/ml
- ConjugateUnconjugated
- Gene ID604
- Target nameBCL6
- Target descriptionBCL6 transcription repressor
- Target synonymsBCL5, BCL6A, LAZ3, ZBTB27, ZNF51, B-cell lymphoma 6 protein, B cell CLL/lymphoma 6, B-cell lymphoma 5 protein, B-cell lymphoma 6 protein transcript, BCL-5, BCL-6, cys-his2 zinc finger transcription factor, lymphoma-associated zinc finger gene on chromosome 3, protein LAZ-3, zinc finger and BTB domain-containing protein 27, zinc finger protein 51, zinc finger transcription factor BCL6S
- HostRabbit
- IsotypeIgG
- Protein IDP41182
- Protein NameB-cell lymphoma 6 protein
- Scientific DescriptionThe protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal POZ domain. This protein acts as a sequence-specific repressor of transcription, and has been shown to modulate the transcription of START-dependent IL-4 responses of B cells. This protein can interact with a variety of POZ-containing proteins that function as transcription corepressors. This gene is found to be frequently translocated and hypermutated in diffuse large-cell lymphoma (DLCL), and may be involved in the pathogenesis of DLCL. Alternatively spliced transcript variants encoding different protein isoforms have been found for this gene. [provided by RefSeq]
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Liu J, Li J, Yin J. Changes of allergic inflammation and immunological parameters after Alt a 1 and A. alternata immunotherapy in mice. World Allergy Organ J. 2023,16(8):100807. doi: 10.1016/j.waojou.2023.100807Read this paper
- Chen D, Xiong XQ, Zang YH, et al. BCL6 attenuates renal inflammation via negative regulation of NLRP3 transcription. Cell Death Dis. 2017,8(10):e3156. doi: 10.1038/cddis.2017.567Read this paper




![IHC-P analysis of human diffuse large B cell lymphoma using GTX01937 BCL6 antibody [LN22]. The majority of neoplastic cells show a moderate to strong nuclear staining reaction.](https://www.genetex.com/upload/website/prouct_img/normal/GTX01937/GTX01937_20200811_IHC-P_105_w_23053121_903.webp)