![WB analysis of human RPE cell lysate using GTX30219 Bestrophin antibody[E6-6]. WB analysis of human RPE cell lysate using GTX30219 Bestrophin antibody[E6-6].](https://www.genetex.com/upload/website/prouct_img/normal/GTX30219/GTX30219_1367_WB_w_23060722_540.webp)
WB analysis of human RPE cell lysate using GTX30219 Bestrophin antibody[E6-6].
Bestrophin antibody [E6-6]
GTX30219
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityCanine, Human, Porcine, Primate
TargetBEST1
Overview
- SupplierGeneTex
- Product NameBestrophin antibody [E6-6]
- Delivery Days Customer9
- Antibody SpecificityWe do not recommend use of this product for Rat.
- Application Supplier NoteWB: 1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDE6-6
- ConjugateUnconjugated
- Gene ID7439
- Target nameBEST1
- Target descriptionbestrophin 1
- Target synonymsARB; BEST; Best disease; Best1V1Delta2; bestrophin-1; BMD; RP50; TU15B; vitelliform macular dystrophy protein 2; VMD2
- HostMouse
- IsotypeIgG1
- Protein IDO76090
- Protein NameBestrophin-1
- Scientific DescriptionBest macular dystrophy (BMD) or vitelliform macular dystrophy (VMD2), is an autosomal form of macular degeneration, characterized by a depressed light peak in the electrooculogram (EOG). It is inherited and has an early onset. Bestrophin is a 68 kDa basolateral plasma membrane protein encoded by the VMD2 gene. Bestrophins function is still unknown, but data suggests that it is a chloride channel that plays a role in generating the altered EOG in Best disease patients. In addition, Bestrophin is a useful biochemical and histological marker of RPE (retinal pigment epithelial cells) cells.
- ReactivityCanine, Human, Porcine, Primate
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203