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beta Tubulin antibody

GTX107175
GeneTex
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Zebra Fish
TargetTUBB1
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Overview

  • Supplier
    GeneTex
  • Product Name
    beta Tubulin antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID81027
  • Target name
    TUBB1
  • Target description
    tubulin beta 1 class VI
  • Target synonyms
    tubulin beta-1 chain; tubulin, beta 1
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ9H4B7
  • Protein Name
    Tubulin beta-1 chain
  • Scientific Description
    Microtubules are involved in a wide variety of cellular processes, including mitosis, morphogenesis, platelet formation, and mobility of cilia and flagella. Circulating platelets carry a single marginal microtubule coil that is wound in 8 to 12 turns and is responsible for platelet shape. TUBB1 is the major beta-tubulin expressed in platelets and megakaryocytes and is required for optimal platelet assembly (Wang et al., 1986 [PubMed 3782288]; Schulze et al., 2004 [PubMed 15315966]).[supplied by OMIM]
  • Reactivity
    Human, Mouse, Zebra Fish
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • RhoA/Cdc42 signaling drives cytoplasmic maturation but not endomitosis in megakaryocytes. Heib T et al., 2021 May 11, Cell Rep
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  • TFEB regulates pluripotency transcriptional network in mouse embryonic stem cells independent of autophagy-lysosomal biogenesis. Tan A et al., 2021 Apr 1, Cell Death Dis
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  • Forming megakaryocytes from murine-induced pluripotent stem cells by the inducible overexpression of supporting factors. Cullmann K et al., 2021 Jan, Res Pract Thromb Haemost
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  • Phosphorylation by NLK inhibits YAP-14-3-3-interactions and induces its nuclear localization. Moon S et al., 2017 Jan, EMBO Rep
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  • Lactate/pyruvate transporter MCT-1 is a direct Wnt target that confers sensitivity to 3-bromopyruvate in colon cancer. Sprowl-Tanio S et al., 2016, Cancer Metab
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  • A novel Bcr-Abl-mTOR-eIF4A axis regulates IRES-mediated translation of LEF-1. Tsai BP et al., 2014 Nov, Open Biol
    Read more