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BMP4 antibody

GTX100875
GeneTex
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetBMP4
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Overview

  • Supplier
    GeneTex
  • Product Name
    BMP4 antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:10000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    2.02 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID652
  • Target name
    BMP4
  • Target description
    bone morphogenetic protein 4
  • Target synonyms
    BMP2B; BMP2B1; bone morphogenetic protein 2B; bone morphogenetic protein 4; MCOPS6; OFC11; ZYME
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP12644
  • Protein Name
    Bone morphogenetic protein 4
  • Scientific Description
    This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein regulates heart development and adipogenesis. Mutations in this gene are associated with orofacial cleft and microphthalmia in human patients. The encoded protein may also be involved in the pathology of multiple cardiovascular diseases and human cancers. [provided by RefSeq, Jul 2016]
  • Reactivity
    Human, Mouse, Rat
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Immunohistochemical analysis revealed the expression of bone morphogenetic proteins-4, 6, 7, and 9 in human induced membrane samples treated with the Masquelet technique. Niikura T et al., 2022 Jan 15, J Orthop Surg Res
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  • Prostate cancer-secreted CCN3 uses the GSK3beta and beta-catenin pathways to enhance osteogenic factor levels in osteoblasts. Chen PC et al., 2021 Mar, Environ Toxicol
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  • Dengue Virus Infects Primary Human Hair Follicle Dermal Papilla Cells. Wei KC et al., 2018, Front Cell Infect Microbiol
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  • Evaluation and Immunolocalization of BMP4 and FGF8 in Odontogenic Cyst and Tumors. Swarup N et al., 2018, Anal Cell Pathol (Amst)
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  • Identification of the common regulators for hepatocellular carcinoma induced by hepatitis B virus X antigen in a mouse model. Lu JW et al., 2012 Jan, Carcinogenesis
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