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BMP4 antibody

Name: BMP4 antibody
SKU: GTX100875_G10
Availability: BackOrder

GTX100875

ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Product group Antibodies

ReactivityHuman, Mouse, Rat

TargetBMP4

Overview

Supplier
GeneTex
Product Name
BMP4 antibody
Delivery Days Customer
9
Application Supplier Note
WB: 1:500-1:10000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Applications
Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Certification
Research Use Only
Clonality
Polyclonal
Concentration
2.02 mg/ml
Conjugate
Unconjugated
Gene ID652
Target name
BMP4
Target description
bone morphogenetic protein 4
Target synonyms
BMP2B, BMP2B1, MCOPS6, OFC11, ZYME, bone morphogenetic protein 4, bone morphogenetic protein 2B
Host
Rabbit
Isotype
IgG
Protein IDP12644
Protein Name
Bone morphogenetic protein 4
Scientific Description
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein regulates heart development and adipogenesis. Mutations in this gene are associated with orofacial cleft and microphthalmia in human patients. The encoded protein may also be involved in the pathology of multiple cardiovascular diseases and human cancers. [provided by RefSeq, Jul 2016]
Reactivity
Human, Mouse, Rat
Storage Instruction
-20°C or -80°C,2°C to 8°C
UNSPSC
12352203

Niikura T, Oda T, Jimbo N, et al. Immunohistochemical analysis revealed the expression of bone morphogenetic proteins-4, 6, 7, and 9 in human induced membrane samples treated with the Masquelet technique. J Orthop Surg Res. 2022,17(1):29. doi: 10.1186/s13018-022-02922-y
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Chen PC, Liu SC, Lin TH, et al. Prostate cancer-secreted CCN3 uses the GSK3β and β-catenin pathways to enhance osteogenic factor levels in osteoblasts. Environ Toxicol. 2021,36(3):425-432. doi: 10.1002/tox.23048
Read this paper
Wei KC, Huang MS, Chang TH. Dengue Virus Infects Primary Human Hair Follicle Dermal Papilla Cells. Front Cell Infect Microbiol. 2018,8:268. doi: 10.3389/fcimb.2018.00268
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Swarup N, Nayak MT, Chowdhary Z, et al. Evaluation and Immunolocalization of BMP4 and FGF8 in Odontogenic Cyst and Tumors. Anal Cell Pathol (Amst). 2018,2018:1204549. doi: 10.1155/2018/1204549
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Lu JW, Hsia Y, Yang WY, et al. Identification of the common regulators for hepatocellular carcinoma induced by hepatitis B virus X antigen in a mouse model. Carcinogenesis. 2012,33(1):209-19. doi: 10.1093/carcin/bgr224
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