Boc-Leu-Arg-Arg-AMC [109358-46-5]

AdipoGen Life Sciences

Boc-Leu-Arg-Arg-AMC

10

109358-46-5

Research Use Only

>98%

C33H52N10O7 . C2H4O2

700.8 . 60.1

Chemical. CAS: 109358-46-5 (free base). Formula: C33H52N10O7 . C2H4O2. MW: 700.8 . 60.1. Fluorogenic tri-peptide substrate for measuring the trypsin-like peptidase activity of the 20S proteasome. Substrate for the Kex2 endopeptidase from S. Cervisiae, which has substrate specificity toward the C-terminal side of LR, PR and RR sequences. Can be cleaved by Kallikrein 5 with a P1 site preference for basic residues (R and K). Excitation: 380nm. Emission: 460nm. This substrate is useful for inhibitor screening and kinetic analysis. - Fluorogenic tri-peptide substrate for measuring the trypsin-like peptidase activity of the 20S proteasome. Substrate for the Kex2 endopeptidase from S. Cervisiae, which has substrate specificity toward the C-terminal side of LR, PR and RR sequences. Can be cleaved by Kallikrein 5 with a P1 site preference for basic residues (R and K). Excitation: 380nm. Emission: 460nm. This substrate is useful for inhibitor screening and kinetic analysis.

Cl.CC(C)C[C@H](NC(=O)OC(C)(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)NC(CCCNC(N)=N)C(=O)NC1=CC2=C(C=C1)C(C)=CC(=O)O2

-20°C,2°C to 8°C

12352200